Author | Matos, Márcia A. D. | |
Author | Reis, Nádia Rúbia S. | |
Author | Kozlowski, Aline G. | |
Author | Teles, Sheila A. | |
Author | Castro, Ana Rita C. Motta | |
Author | Mello, Francisco C. A. | |
Author | Gomes, Selma A. | |
Author | Martins, Regina M. B. | |
Access date | 2018-07-30T17:57:53Z | |
Available date | 2018-07-30T17:57:53Z | |
Document date | 2009 | |
Citation | MATOS, Márcia A. D. et al. Epidemiological study of hepatitis A, B and C in the largest Afro-Brazilian isolated community. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 103, p.899-905, 2009. | pt_BR |
ISSN | 0035-9203 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/27722 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Vírus da Hepatite B | pt_BR |
Subject in Portuguese | Vírus da Hepatite A | pt_BR |
Subject in Portuguese | Vírus da Hepatite C | pt_BR |
Subject in Portuguese | Prevalência | pt_BR |
Subject in Portuguese | genótipos | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | Epidemiological study of hepatitis A, B and C in the largest Afro-Brazilian isolated community | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.trstmh.2009.01.013 | |
Abstract | This study was conducted to estimate the prevalence and molecular epidemiological features of viral hepatitis A, B and C in the Kalunga population, which represents the largest Afro-Brazilian isolated community. Among 878 individuals studied, the overall prevalence of anti-hepatitis A virus antibodies was 80.9%, with a significant rise from 44.8% to near 100% between the first and fourth decade of life. Rates for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc) of 1.8% and 35.4%, respectively, were found. Increasing age, male gender, illiteracy and history of multiple sexual partners were associated with hepatitis B virus (HBV) infection. An occult HBV infection rate of 1.7% (5/295) was found among anti-HBc-positive individuals. HBV genotype A (subtype Aa) was dominant in this community. Only 5/878 individuals (0.6%) were positive for anti-hepatitis C virus (HCV). HCV RNA was detected in three of them, who were infected with genotype 1 (subtype 1a). These findings point out high, intermediate and low endemicity for hepatitis A, B and C, respectively, in the Kalunga community in Brazil. Circulation of HBV genotype A (subtype Aa) in this Afro-Brazilian isolated community indicates the introduction of this virus during the slave trade from Africa to Brazil. | pt_BR |
Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
Affilliation | Universidade Federal de Mato Grosso do Sul. Departamento de Farmácia Bioquímica. Campo Grande, MS, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | pt_BR |
Subject | Hepatitis A virus | pt_BR |
Subject | Hepatitis B virus | pt_BR |
Subject | Hepatitis C virus | pt_BR |
Subject | prevalence | pt_BR |
Subject | Genotype | pt_BR |
Subject | Brazil | pt_BR |
e-ISSN | 1878-3503 | |
Embargo date | 2030-01-01 | |