Please use this identifier to cite or link to this item: http://www.arca.fiocruz.br/handle/icict/2767
Title: Evaluation of four whole-cell leptospira-based serological tests for diagnosis of urban leptospirosis
Authors: McBride, Alan John Alexander
Santos, Balbino L. dos
Queiroz, Adriano
Santos, Andréia Carvalho dos
Hartskeerl, Rudy A
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Royal Tropical Institute (KIT). Department of Biomedical Research. Amsterdam, The Netherlands
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Cornell University. Weill Medical College. Division of International Medicine and Infectious Disease. New York, NY, USA
Abstract: Four serologic assays for leptospirosis had sensitivities of 72 to 88% and specificities of 88 to 100% in the setting of highly endemic urban transmission, indicating that assays using enzyme-linked immunosorbency and rapid formats may be used as alternatives to the microscopic agglutination test for diagnosing urban leptospirosis. Testing a second sample will be required in cases with an initial negative result, since sensitivity was low (46 to 68%) during the first week of illness.
Keywords: Leptospirosis
Human Leptospirosis
Diagnosis
keywords: Leptospirose
Leptospirose Humana
Diagnóstico
DeCS: Leptospirose
/diagnóstico
Issue Date: 2007
Publisher: American Society for Microbiology (ASM)
Citation: MCBRIDE, A. J. A. et al. Evaluation of four whole-cell leptospira-based serological tests for diagnosis of urban leptospirosis. Clinical and Vaccine Immunology, v.14, n.9, p.1245–1248, 2007.
Description: Agradecimentos ao HemoCentro do Estado da Bahia (HEMOBA) pelo fornecimento de amostras de doadores de sangue, PanBio, Inc., e Bio-Manguinhos por doar os ensaios utilizados neste estudo. Agradecimentos também a Flávia Cruz McBride, Éverton Fagonde da Silva, Deborah Bittencourt Mothé Fraga, Josilene Borges Torres Lima, Cleiton Silva Santos e Jefferson Alves pela assistência técnica durante a avaliação.
ISSN: 1556-6811
Copyright: open access
Appears in Collections:IGM - Artigos de Periódicos

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