Author | Sánchez, A. | |
Author | Huber, F. D. | |
Author | Massari, V. | |
Author | Barreto, A. | |
Author | Camacho, L. A. B. | |
Author | Cesconi, V. | |
Author | Saad, M. H. | |
Author | Larouze, B. | |
Access date | 2018-04-26T12:18:43Z | |
Available date | 2018-04-26T12:18:43Z | |
Document date | 2012 | |
Citation | SÀNCHEZ, A. et al. Extensive Mycobacterium tuberculosis circulation in a highly endemic prison and the need for urgent environmental interventions. Epidemiol. Infect., v.140, p.1853-1861, 2012. | pt_BR |
ISSN | 0950-2688 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/26120 | |
Language | eng | pt_BR |
Publisher | Cambridge University Press | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Tuberculose | pt_BR |
Subject in Portuguese | Epidemiologia molecular | pt_BR |
Subject in Portuguese | Prisões | pt_BR |
Subject in Portuguese | Mycobacterium tuberculosis | pt_BR |
Title | Extensive Mycobacterium tuberculosis circulation in a highly endemic prison and the need for urgent environmental interventions | pt_BR |
Type | Article | pt_BR |
DOI | 10.1017/S0950268811002536 | |
Abstract | Aimed at assessing the circulation of Mycobacterium tuberculosis in a highly endemic prison, this 13-month prospective study was performed on strains isolated from tuberculosis (TB) cases detected passively and actively. We used X-ray screening of newly admitted inmates and mass screening at the beginning of the study and again 1 year later. Of the 94 strains genotyped by restriction fragment-length polymorphism, 79 (84·0%) belonged to one of the 12 identified clusters (2-21 strains each), including two main clusters (18 and 21 cases, respectively). A history of TB treatment was reported in 22/79 (27·8%) clustered cases. Time-space distribution of clustered cases was predominantly consistent with transmission, in micro-epidemics. Given the dominant pattern of exogenous infection and the extensive strain circulation, effective TB control should emphasize reduction of overcrowding and improvement of environmental measures as a complement to detection and treatment of cases. | pt_BR |
Affilliation | Secretaria de Estado de Administração Penitenciária. Coordenação de Gestão em Saúde Penitenciária. Programa de Controle de Tuberculose. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Microbiologia Celular. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | INSERM U707., UPMC, F-75012. Paris, France. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Departamento de Epidemiologia e Métodos Quantitativos. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Secretaria de Estado de Administração Penitenciária. Coordenação de Gestão em Saúde Penitenciária. Programa de Controle de Tuberculose. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Microbiologia Celular. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | INSERM U707., UPMC, F-75012. Paris, France / Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Departamento de Epidemiologia e Métodos Quantitativos. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Molecular epidemiology | pt_BR |
Subject | Mycobacterium tuberculosis | pt_BR |
Subject | prisons | pt_BR |
Subject | RFLP | pt_BR |
Subject | Tuberculosis | pt_BR |
e-ISSN | 1469-4409 | |
Embargo date | 2030-01-01 | |