Author | Guevara, Ana | |
Author | Cabello, Robinson | |
Author | Woelber, Linn | |
Author | Moreira Junior, Edson Duarte | |
Author | Joura, Elmar | |
Author | Reich, Olaf | |
Author | Shields, Christine | |
Author | Ellison, Misoo C | |
Author | Joshi, Amita | |
Author | Luxembourg, Alain | |
Access date | 2018-04-23T16:39:30Z | |
Available date | 2018-04-23T16:39:30Z | |
Document date | 2017 | |
Citation | GUEVARA, A. et al. Antibody persistence and evidence of immune memory at 5years following administration of the 9-valent HPV vaccine. Vaccine, v. 35, p. 5050–5057, 2017. | pt_BR |
ISSN | 0264-410X | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/26034 | |
Sponsorship | Merck & Co., Inc., Kenilworth, NJ, USA. | pt_BR |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Papiloma virus humano | pt_BR |
Subject in Portuguese | Vacinas contra HPV | pt_BR |
Subject in Portuguese | Imunogenicidade | pt_BR |
Subject in Portuguese | Ensaio clínico | pt_BR |
Title | Antibody persistence and evidence of immune memory at 5years following administration of the 9-valent HPV vaccine | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.vaccine.2017.07.017 | |
Abstract | The 9-valent HPV (9vHPV) vaccine was developed to prevent infection and disease related to 9 HPV types (HPV6/11/16/18/31/33/45/52/58) which cause approximately 90% of cervical cancers, HPV-related vulvar, vaginal and anal cancers, and genital warts worldwide. In a pivotal efficacy study, the 9vHPV vaccine prevented infection and disease due to the 9 vaccine types. Duration of protection remains to be determined. Vaccines that induce long-term protection are generally characterized by the generation of immune memory. The purpose of this report is to assess the persistence of HPV antibody response and existence of immune memory at 5years post-vaccination. | pt_BR |
Affilliation | Pablo Tobon Uribe Hospital. Research Unit. Medellin, Antioquia, Colombia | pt_BR |
Affilliation | Vía Libre CRS. Lima, Peru | pt_BR |
Affilliation | University Medical Center Hamburg-Eppendorf. Hamburg, Germany | pt_BR |
Affilliation | Associação Obras Sociais Irma Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Medical University of Vienna. Comprehensive Cancer Center. Vienna, Austria | pt_BR |
Affilliation | Medical University of Graz. Department of Obstetrics & Gynecology. Graz, Austria | pt_BR |
Affilliation | Merck & Co. Kenilworth, NJ, USA | pt_BR |
Affilliation | Merck & Co. Kenilworth, NJ, USA | pt_BR |
Affilliation | Merck & Co. Kenilworth, NJ, USA | pt_BR |
Affilliation | Merck & Co. Kenilworth, NJ, USA | pt_BR |
Subject | Human papillomavirus | pt_BR |
Subject | 9vHPV vaccine | pt_BR |
Subject | Immunogenicity | pt_BR |
Subject | Clinical trial | pt_BR |