Author | Gomes Filho, Isaac Suzart | |
Author | Pereira, Eliesita Costa | |
Author | Cruz, Simone Seixas da | |
Author | Adan, Luis Fernando Fernandes | |
Author | Vianna, Maria Isabel Pereira | |
Author | Soares, Johelle de Santana Passos | |
Author | Trindade, Soraya Castro | |
Author | Oliveira, Ernesto P | |
Author | Oliveira, Michelle Teixeira | |
Author | Cerqueira, Eneida de Moraes Marcilio | |
Author | Pereira, Antonio Luis | |
Author | Barreto, Maurício Lima | |
Author | Seymour, Gregory John | |
Access date | 2018-03-01T16:19:05Z | |
Available date | 2018-03-01T16:19:05Z | |
Document date | 2016 | |
Citation | GOMES FILHO, I. S. et al. Relationship Among Mothers' Glycemic Level, Periodontitis, and Birth Weight. Journal of Periodontology, v. 87, p. 238-247, 2016. | pt_BR |
ISSN | 0022-3492 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/25019 | |
Description | BARRETO, Mauricio Lima. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
Sponsorship | Foundation of the State of Bahia, National Council for Scientific and Technological Development, and Feira de Santana State University | pt_BR |
Language | eng | pt_BR |
Publisher | American Academy of Periodontology | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Epidemiologia | pt_BR |
Subject in Portuguese | Hemoglobina A, glicosilada | pt_BR |
Subject in Portuguese | Infantil | pt_BR |
Subject in Portuguese | Baixo peso ao nascer | pt_BR |
Subject in Portuguese | Periodontite | pt_BR |
Subject in Portuguese | Gravidez | pt_BR |
Title | Relationship Among Mothers' Glycemic Level, Periodontitis, and Birth Weight | pt_BR |
Type | Article | pt_BR |
DOI | 10.1902/jop.2015.150423 | |
Abstract | The aim of this study is to determine the influence of glycemic level on the relationship between periodontitis and low birth weight (LBW). Methods: A case-control study was conducted with 372 females divided into cases (109 mothers of
newborns with birth weight <2,500 g) and controls (263 mothers of newborns with birth weight ‡2,500 g).
The birth weight of children was obtained from medical records, whereas information on sociodemographic,
lifestyle, and health characteristics of the participants was obtained through an interview. Glycated
hemoglobin (HbA1c) levels were measured, and probing depth, clinical attachment levels, and bleeding on
probing were used to determine the periodontal status. Results were analyzed using logistic regression.
Results: The likelihood of having children with LBW among the mothers with periodontitis was six times
greater than that observed among mothers without periodontitis (adjusted odds ratio [ORadjusted] = 6.02,
95% confidence interval [CI] = 2.47 to 15.17), even after adjustment. There was also a strong, statistically
significant relationship between periodontitis and LBW in both the normal glycemic–level group (HbA1c
levels <5.6%, unadjusted odds ratio [ORunadjusted] = 8.30, 95% CI = 3.56 to 19.35) and the high glycemic–level
group (HbA1c levels ‡5.6% and <6.5%, ORunadjusted = 5.73, 95% CI = 1.75 to 18.70). After adjustment for
confounders, the magnitude of the association continued to be strong in the normal glycemic–level group
(ORadjusted = 7.59, 95% CI = 2.7 to 24.28), an increase of 25% when compared to the main association measurement.
In those with high glycemic levels (ORadjusted = 4.03, 95% CI = 0.81 to 19.96), the OR decreased almost
50%, and the association lost statistical significance.
Conclusion: Periodontitis and glycemic levels appeared to have opposing influences on birth weight, with periodontitis
being associated with LBW and the magnitude of the association being altered depending on maternal
blood glucose level. | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil / Federal University of Recôncavo of Bahia. Santo Antonio de Jesus, BA, Brasil | pt_BR |
Affilliation | Federal University of Bahia. Department of Medicine. Salvador, BA, Brasil | pt_BR |
Affilliation | Federal University of Bahia. Department of Preventive Dentistry. Salvador, BA, Brasil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brasil / Federal University of Bahia. Department of Preventive Dentistry. Salvador, BA, Brasil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil | pt_BR |
Affilliation | Federal University of Bahia. Department of Pharmacy. Salvador, BA, Brazil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil | pt_BR |
Affilliation | Feira de Santana State University. Department of Health. Salvador, BA, Brazil | pt_BR |
Affilliation | Federal University of Maranhão. Department of Dentistry. São Luís, MA, Brazil | pt_BR |
Affilliation | Federal University of Bahia. Department of Public Health. Salvador, BA, Brazil | pt_BR |
Affilliation | University of Otago. Sir John Walsh Research Institute. Dunedin, New Zealand | pt_BR |
Subject | Epidemiology | pt_BR |
Subject | Hemoglobin A | pt_BR |
Subject | Glycosylated | pt_BR |
Subject | Infant | pt_BR |
Subject | Low birth weight | pt_BR |
Subject | Periodontitis | pt_BR |
Subject | Pregnancy | pt_BR |