Author | Ribeiro, Christiane Fernandes | |
Author | Lopes, Vânia Glória Silami | |
Author | Brasil, Patrícia | |
Author | Pires, Andrea Rodrigues Cordovil | |
Author | Rohloff, Roger | |
Author | Nogueira, Rita Maria Ribeiro | |
Access date | 2018-02-11T13:25:13Z | |
Available date | 2018-02-11T13:25:13Z | |
Document date | 2017 | |
Citation | RIBEIRO, Christiane Fernandes et al. Dengue infection in pregnancy and its impact on the placenta. International Journal of Infectious Diseases, v. 55, p. 109-112, 2017. | pt_BR |
ISSN | 1201-9712 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/24801 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Dengue | pt_BR |
Subject in Portuguese | Gravidez | pt_BR |
Subject in Portuguese | Transmissão vertical | pt_BR |
Subject in Portuguese | Placenta | pt_BR |
Title | Dengue infection in pregnancy and its impact on the placenta | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.ijid.2017.01.002 | |
Abstract | A histopathological and immunohistochemical study was conducted in placental tissues and retained products of conception from 24 patients with confirmed dengue infection during pregnancy. The immunohistochemical assay was positive for dengue virus in 19 placental and three ovular remnants analyzed. The light microscopic findings were signs of hypoxia, choriodeciduitis, deciduitis and intervillositis and the viral antigens were found in cytoplasmic of the trophoblast, villous stroma and decidua. Our results suggest that immunohistochemistry could be used as a laboratory confirmation method for dengue in pregnant women, especially in endemic areas when embedded material is the only material available. | pt_BR |
Affilliation | Universidade Federal Fluminense. Departamento Materno-Infantil. Niterói, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal Fluminense. Departamento de Patologia. Niterói, RJ, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Perinatal Laranjeiras. Unidade de Cuidados Intensivos Materno-fetal. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivirus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Dengue | pt_BR |
Subject | Pregnancy | pt_BR |
Subject | Vertical transmission | pt_BR |
Subject | Placenta | pt_BR |
e-ISSN | 1878-3511 | |
Embargo date | 2030-01-01 | |