Author | Cortes, Vanessa Faria | |
Author | Taveira, Angela | |
Author | Cruz, Helena Medina | |
Author | Reis, Amanda Alves | |
Author | Cezar, Jéssica Silva | |
Author | Silva, Brener Santos | |
Author | D'Assunção, Cintia Feliciano | |
Author | Lampe, Elisabeth | |
Author | Villar, Livia Melo | |
Access date | 2018-02-06T11:56:29Z | |
Available date | 2018-02-06T11:56:29Z | |
Document date | 2017 | |
Citation | CORTES, Vanessa Faria; et al. Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination. Rev Inst Med Trop São Paulo. v.59, e47, 5p, 2017. | pt_BR |
ISSN | 0036-4665 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/24727 | |
Language | eng | pt_BR |
Publisher | Universidade de São Paulo | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Virus da Hepatite C | pt_BR |
Subject in Portuguese | Vírus da hepatite B | pt_BR |
Subject in Portuguese | Prevalência | pt_BR |
Subject in Portuguese | Saliva | pt_BR |
Subject in Portuguese | Pacientes alcoólicos | pt_BR |
Title | Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination | pt_BR |
Type | Article | pt_BR |
DOI | 10.1590/S1678-9946201759047 | |
Abstract | Drug users have been reported to have an increased risk for acquisition of viral hepatitis. This study aims to evaluate the prevalence of HBV and HCV infection and usefulness of saliva for HBsAg and anti-HCV detection in alcoholic patients.A total of 90 alcoholic patients were recruited in 2013. HBsAg and anti-HCV were tested in serum and saliva, anti-HBc and anti-HBs were tested in serum using commercial enzyme immunoassays (EIA).Using serum samples, anti-HCV, HBsAg, anti-HBc and anti-HBs prevalences were 5.6%, 0%, 15.7%, and 29.2%. HBsAg detection in saliva showed 100% of specificity and anti-HCV detection demonstrated 100% of sensitivity and 94.7% of specificity. Low prevalence of HBV and high prevalence of anti-HCV were found and reinforced the recommendation of HBV vaccination to avoid the acute and chronic cases and HCV screening in this group to identify cases for antiviral therapy. Saliva samples could be used for anti-HCV detection in this population, what could increase the diagnosis access. | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil. | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil. | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil. | pt_BR |
Affilliation | Universidade Federal de São João del Rei. Laboratório de Bioquímica Celular. São João del Rei, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Hepatitis C virus | pt_BR |
Subject | Hepatitis B virus | pt_BR |
Subject | Prevalence | pt_BR |
Subject | Saliva | pt_BR |
Subject | Alcoholic patients | pt_BR |
e-ISSN | 1678-9946 | |