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https://www.arca.fiocruz.br/handle/icict/20964
FACTORS ASSOCIATED WITH TREATMENT FOR LATENT TUBERCULOSIS IN PERSONS LIVING WITH HIV/AIDS
Factores asociados al tratamiento de la tuberculosis latente en personas viviendo con VIH/SIDA
Antitubercular Agents
Antitubercular Agents
therapeutic use
Isoniazid
Latent Tuberculosis
complications
diagnosis
drug therapy
epidemiology
Male
Risk factors
Prospective Studies
Humans
Infecções por HIV
Antituberculosos
Feminino
Isoniazida
Tuberculose Latente
Masculino
Estudos prospectivos
Fatores de risco
Humanos
Alternative title
Fatores associados ao tratamento da tuberculose latente em pessoas vivendo com HIV/AIDSFactores asociados al tratamiento de la tuberculosis latente en personas viviendo con VIH/SIDA
Author
Affilliation
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil
Abstract
The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study's most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.
Keywords
AdultAntitubercular Agents
Antitubercular Agents
therapeutic use
Isoniazid
Latent Tuberculosis
complications
diagnosis
drug therapy
epidemiology
Male
Risk factors
Prospective Studies
Humans
DeCS
AdultosInfecções por HIV
Antituberculosos
Feminino
Isoniazida
Tuberculose Latente
Masculino
Estudos prospectivos
Fatores de risco
Humanos
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