Author | Menezes, Heverly Suzany Gouveia | |
Author | Chalegre, Karlos Diogo de Melo | |
Author | Romão, Tatiany Patrícia | |
Author | Oliveira, Cláudia Maria Fontes | |
Author | de-Melo-Neto, Osvaldo Pompílio | |
Author | Silva-Filha, Maria Helena Neves Lobo | |
Access date | 2017-09-05T18:53:50Z | |
Available date | 2017-09-05T18:53:50Z | |
Document date | 2016 | |
Citation | MENEZES, H. S. G. et al. A new allele conferring resistance to Lysinibacillus sphaericus is detected in low frequency in Culex quinquefasciatus field populations. Parasites & Vectors, v. 9, p. 70, 4 fev. 2016. | pt_BR |
ISSN | 1756-3305 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/20923 | |
Language | por | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Bacillaceae | pt_BR |
Subject in Portuguese | imunologia | pt_BR |
Subject in Portuguese | Toxinas Bacterianas | pt_BR |
Subject in Portuguese | Genes de Insetos | pt_BR |
Title | A new allele conferring resistance to Lysinibacillus sphaericus is detected in low frequency in Culex quinquefasciatus field populations | pt_BR |
Type | Article | pt_BR |
DOI | 10.1186/s13071-016-1347-2 | |
Abstract | The Cqm1 α-glucosidase of Culex quinquefasciatus larvae acts as the midgut receptor for the binary toxin of the biolarvicide Lysinibacillus sphaericus. Mutations within the cqm1 gene can code for aberrant polypeptides that can no longer be properly expressed or bind to the toxin, leading to insect resistance. The cqm1 REC and cqm1 REC-2 alleles were identified in a laboratory selected colony and both displayed mutations that lead to equivalent phenotypes of refractoriness to L. sphaericus. cqm1 REC was first identified as the major resistance allele in this colony but it was subsequently replaced by cqm1 REC-2 , suggesting the better adaptive features of the second allele. The major aim of this study was to evaluate the occurrence of cqm1 REC-2 and track its origin in field populations where cqm1 REC was previously identified. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil | pt_BR |
Subject | Bacillaceae | pt_BR |
Subject | immunology | pt_BR |
Subject | Bacterial Toxins | pt_BR |
Subject | toxicity | pt_BR |
Subject | Culex | pt_BR |
Subject | microbiology | pt_BR |
Subject | Genes, Insect | pt_BR |
Subject | Insecticide Resistance | pt_BR |
Subject | Insecticides | pt_BR |
Subject | Multiplex Polymerase Chain Reaction | pt_BR |
Subject | Sequence Analysis, DNA | pt_BR |
Subject | Cities | pt_BR |
Subject | Brazil | pt_BR |
Subject | Alleles | pt_BR |
Subject | Animals | pt_BR |
DeCS | Bacillaceae | pt_BR |
DeCS | Toxinas Bacterianas | pt_BR |
DeCS | Culex | pt_BR |
DeCS | Genes de Insetos | pt_BR |
DeCS | Inseticidas | pt_BR |
DeCS | Resistência a Inseticidas | pt_BR |
DeCS | Brasil | pt_BR |
DeCS | Cidades | pt_BR |
DeCS | Alelos | pt_BR |
DeCS | Animais | pt_BR |
DeCS | Reação em Cadeia da Polimerase Multiplex | pt_BR |
DeCS | Análise de Sequência de DNA | pt_BR |