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https://www.arca.fiocruz.br/handle/icict/20514
MALIGNANT ADENOMYO-EPITHELIOMA IN A FELINE MAMMARY GLAND
Author
Affilliation
State University. School of Agricultural and Veterinary Sciences of the São Paulo. Department of Veterinary Clinic and Surgery. Jaboticabal Campus, SP, Brasil / Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Veterinary Hospital, Veterinary School. Biological Science Institute. Department of Veterinary Clinic and Surgery. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Veterinary Hospital, Veterinary School. Biological Science Institute. Department of Veterinary Clinic and Surgery. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Federal University of Minas Gerais. Biological Science Institute. Laboratory of Comparative Pathology. Department of General Pathology. Belo Horizonte, MG, Brasil
Abstract
Mammary neoplasms are the third most frequent tumor in felines. We describe
clinical, histopathological, and immuno-histochemical findings from a malignant
adenomyo-epithelioma (MA) from a domestic queen. The cat presented with
mammary masses and underwent radical unilateral mastectomy followed by
chemotherapy. The tumor recurred and the animal survived 125 days but then died.
Microscopy revealed a highly cellular malignant myoepithelial solid cell proliferation
pattern with moderate pleomorphism and malignant epithelial proliferation in a
tubular and papillary arrangement. The myoepithelial nature of the neoplastic cells
was confirmed by p63 target antigen clone test. Based on histopathological and
immunohistochemical findings and histological similarity between women and feline
tumors, a diagnosis of MA was made.
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