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https://www.arca.fiocruz.br/handle/icict/20493
HAM/TSP AND MAJOR DEPRESSION: THE ROLE OF AGE
Depressão
Fatores de risco
Mielopatia associada ao HTLV-1
Author
Affilliation
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Foundation for Science Development. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Foundation for Science Development. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Bahiana School of Medicine and Public Health Salvador. Reference Center for HTLV. Salvador, BA, Brazil
Abstract
To investigate the role of demographic variables in the relationship between the presence of HAM/TSP and current major depression. Methods: It is a cross-sectional study of 108 HTLV-1 infected patients (47 with TSP/HAM)resident of Salvador, Brazil. The Mini International Neuropsychiatric Interview, BrazilianVersion 5 was used to evaluate the presence of depression. Prevalence ratios were used todescribe relationship between HAM/TSP and depression. The HAM/TSP classification wascarried out according to the criteria proposed by Castro-Costa et al.Results: Prevalence of depression was 37.96%. No association was observed between pres-ence of HAM/TSP and diagnosis of current major depression in the global analysis of patients(PR: 0.94; CI 95%: 0.57–1.55). In the stratified analysis, however, greater prevalence of depres-sion was observed amongst individuals with HAM/TSP in the 18–39 age group (PR: 2.59; CI95%: 1.36–4.95).Conclusion: Our findings suggest that age is an effect modifier in the relationship betweenHAM/TSP and depression, and this aspect should be considered in future studies on thetopic.
Keywords in Portuguese
Vírus 1 linfotrópico humanoDepressão
Fatores de risco
Mielopatia associada ao HTLV-1
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