Author | Souza Filho, Job Alves de | |
Author | Barbosa, José Ronaldo | |
Author | Figueiredo, Fabiano Borges | |
Author | Mendes Júnior, Artur Augusto Velho | |
Author | Silva, Shara Regina da | |
Author | Coelho, George Luiz Lins Machado | |
Author | Marcelino, Andreza Pain | |
Access date | 2017-07-10T18:21:21Z | |
Available date | 2017-07-10T18:21:21Z | |
Document date | 2016 | |
Citation | SOUZA FILHO, Job Alves de et al. Performance of Alere™ immunochromathographic test for the diagnosis of canine visceral leishmaniasis. Veterinary Parasitology, v. 225, p. 114-116, 2016. | pt_BR |
ISSN | 0304-4017 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/20029 | |
Language | por | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Alere | pt_BR |
Subject in Portuguese | Leishmaniose visceral canina | pt_BR |
Title | Performance of Alere™ immunochromathographic test for the diagnosis of canine visceral leishmaniasis | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.vetpar.2016.06.011 | |
Abstract | The diagnosis and control of canine visceral leishmaniasis (CVL) has fundamental importance in the control of human visceral leishmaniasis. In this context, the immunochromathographic test (ICT) has emerged as a valuable diagnostic tool. Currently, in Brazil, the algorithm for the diagnosis of CVL uses Dual Path Platform (DPP) ICT as a screening test and ELISA as a confirmatory test. However, the DPP(®) ICT has been facing a problem of insufficient production to meet the national demand. Here, the Alere™ canine visceral leishmaniasis ICT was tested with serum samples from 159 dogs, including symptomatic, asymptomatic and healthy dogs, characterized by DPP(®) ICT and ELISA (panel A), or ELISA and Indirect Immunofluorescence Assay (IFA) (panel B), and parasitological examination as gold standard. In this study, the Alere™ ICT obtained 0.974 sensitivity for panel A and 0.854 sensitivity for panel B. The specificity was 1.0 for both panels. Thus, the Alere™ ICT has potential to be used for the serological diagnosis of CVL. | pt_BR |
Affilliation | Fundação Ezequiel Dias. Instituto Octavio Magalhães. Serviço de Doenças Parasitárias. Laboratório Nacional de Referencia Brasileira de Diagnostico de Leishmaniose Visceral. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Fundação Ezequiel Dias. Instituto Octavio Magalhães. Serviço de Doenças Parasitárias. Laboratorio Nacional de Referencia Brasileira de Diagnostico de Leishmaniose Visceral. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, Minas Gerais, Brazil. | pt_BR |
Affilliation | Fundação Ezequiel Dias. Instituto Octavio Magalhães. Serviço de Doenças Parasitárias. Laboratório Nacional de Referencia Brasileira de Diagnostico de Leishmaniose Visceral. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Fundação Ezequiel Dias. Instituto Octavio Magalhães. Serviço de Doenças Parasitárias. Laboratório Nacional de Referencia Brasileira de Diagnostico de Leishmaniose Visceral. Belo Horizonte, MG, Brazil. | pt_BR |
Subject | Alere | pt_BR |
Subject | Canine visceral leishmaniasis | pt_BR |
Subject | Immunochromathographic test | pt_BR |
Embargo date | 2023-01-01 | |