Author | Silva, Fabiana de Oliveira Lara | |
Author | Michalsky, Érika Monteiro | |
Author | Dias, Consuelo Latorre Fortes | |
Author | Fiuza, Vanessa de Oliveira Pires | |
Author | Pessanha, José Eduardo Marques | |
Author | Silva, Shara Regina da | |
Author | Avelar, Daniel Moreira de | |
Author | Silva, Maiara Alves | |
Author | Lima, Ana Cristina Vianna Mariano da Rocha | |
Author | Costa, Ailton Junior Antunes da | |
Author | Coelho, George Luiz Lins Machado | |
Author | Dias, Edelberto Santos | |
Access date | 2016-01-29T17:40:07Z | |
Available date | 2016-01-29T17:40:07Z | |
Document date | 2015 | |
Citation | SILVA, Fabiana de Oliveira Lara et al. Epidemiological aspects of vector; parasite; and domestic reservoir in areas of recent transmission and no reported human cases of visceral leishmaniasis in Brazil. Acta Tropica, vol. 148, p. 128–136, 2015 | pt_BR |
ISSN | 0001-706X | |
URI | https://www.arca.fiocruz.br/handle/icict/12665 | |
Language | eng | pt_BR |
Publisher | Elsevier Ltda | pt_BR |
Rights | restricted access | pt_BR |
Title | Epidemiological aspects of vector; parasite; and domestic reservoir in areas of recent transmission and no reported human cases of visceral leishmaniasis in Brazil. | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.actatropica.2015.04.002 | |
Abstract | About 97% of the human cases of the American visceral leishmaniasis (VL) occur in Brazil. In the last few years, the disease expanded to medium- and large-sized cities, in which surveillance and control actions have been intensified, in an effort to control VL spreading. Our two-year study was conducted in Belo Horizonte, the sixth most populous city in Brazil, which is endemic for VL. We focused in two particular districts of recent transmission of the disease, with no reported human cases and submitted to minor surveillance and control actions. Our aim was to draw an epidemiological profile of the local situation concerning Lutzomyia vector, Leishmania parasites, and the main domestic reservoirs (dogs). Lutzomyia longipalpis comprised 96.5% of the total phlebotomine sand flies captured and displayed an expressive minimal infection rate by Leishmania infantum (16.7%). Positive correlations were found between the population densities of L. longipalpis, rainfall and temperature. L. infantum was also detected in the cortelezzii complex and, for the first time, in Lutzomyia lloydi. Leishmania braziliensis, an etiological agent of the American cutaneous leishmaniasis, was also identified in L. longipalpis. Among the 1408 dogs serologically tested by standard enzyme-linked and fluorescence immune assays (ELISA/IFA) 3.6% were positive for VL. L. infantum DNA and Leishmania parasites were identified in 100% and 72.5% of the seropositive dogs, respectively. The co-positivity of other diagnostic tests for VL—Leishmania-nested PCR, imprint and myeloculture—was compared to the standard serology. Both symptomatic or asymptomatic dogs displayed an equal average number of positive diagnostic tests for VL. The districts studied display favorable conditions for the rapid spreading of human infection, in terms of L. longipalpis population density, and presence of L. infantum in both vector and main reservoir. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Ezequiel Dias. Diretoria de Pesquisa e Desenvolvimento. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Prefeitura de Belo Horizonte. Secretaria Municipal de Saúde. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Prefeitura de Belo Horizonte. Secretaria Municipal de Saúde. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil | pt_BR |
Subject | Canine visceral leishmaniasis | pt_BR |
Subject | Lutzomyia longipalpis | pt_BR |
Subject | Lutzomyia lloydi | pt_BR |
Subject | cortelezzii complex | pt_BR |
Subject | Leishmania infantum | pt_BR |
Subject | Leishmania braziliensis | pt_BR |