Please use this identifier to cite or link to this item: http://www.arca.fiocruz.br/handle/icict/12141
Title: Haemophilus influenzae meningitis 5 years after introduction of the Haemophilus influenzae type b conjugate vaccine in Brazil.
Authors: Croda, Julio Henrique Rosa
Ramos, João G. R
Matsunaga, James
Queiroz, Adriano
Homma, Akira
Riley, Lee W
Haake, David A
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Veterans Affairs Greater Los Angeles Healthcare System. Division of Infectious Diseases. Los Angeles, California / UCLA School of Medicine. Department of Medicine. Los Angeles, California
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Biomanguinhos. Rio de Janeiro, RJ, Brasil
University of California. School of Public Health. Berkeley, California
Veterans Affairs Greater Los Angeles Healthcare System. Division of Infectious Diseases. Los Angeles, California / UCLA School of Medicine. Department of Medicine. Los Angeles, California
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Weill Medical College of Cornell University. Division of International Medicine and Infectious Disease. Ithaca, New York
Abstract: The long-term impact of Haemophilus influenzae type b (Hib) conjugate vaccine, introduced throughout Latin America in the late 1990s, has not been evaluated. Active surveillance for H. influenzae meningitis was performed from August 9, 1996 to August 8, 2004 in Metropolitan Salvador, Brazil. Five years after the introduction of Hib conjugate vaccine, Hib meningitis incidence decreased from 2.39 to 0.06 cases per 100,000 population (98%) overall, and from 60.9 to 3.1 cases per 100,000 population (95%) in children <1 year of age. A transient serotype replacement phenomenon was observed associated with a small increase of meningitis due to two H. influenzae type a clonal groups. These findings indicate that Hib immunization campaign has led to the virtual elimination of Hib disease in this region
DeCS: Vacinas Anti-Haemophilus
Haemophilus influenzae tipo b/imunologia
Programas de Imunização
Meningite por Haemophilus/epidemiologia
Vigilância da População
Toxoide Tetânico
Vacinas Conjugadas
Vacinas Anti-Haemophilus/administração & dosagem
Criança
Pré-Escolar
Haemophilus influenzae tipo b/classificação
Humanos
Incidência
Lactente
Recém-Nascido
Meningite por Haemophilus/microbiologia
Avaliação de Programas e Projetos de Saúde
Sorotipagem
Toxoide Tetânico/administração & dosagem
Vacinas Conjugadas/administração & dosagem
Issue Date: 2007
Publisher: Elsevier
Citation: CRODA, J. et al. Haemophilus influenzae meningitis 5 years after introduction of the Haemophilus influenzae type b conjugate vaccine in Brazil. Vaccine, v. 25, n. 22, p. 4420-4428, 2007.
DOI: 10.1128/JCM.02344-06
ISSN: 0264-410X
Copyright: open access
Appears in Collections:IGM - Artigos de Periódicos

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