Author | Marcili, Arlei | |
Author | Sperança, Marcia Aparecida | |
Author | Costa, Andréa Pereira da | |
Author | Madeira, Maria de F. | |
Author | Soares, Herbert Sousa | |
Author | Sanches, Camila de Oliveira Campos Camargo | |
Author | Acosta, Igor da Cunha Lima | |
Author | Girotto, Aline | |
Author | Minervino, Antonio Humberto Hamad | |
Author | Horta, Maurício C. | |
Author | Shaw, Jeffrey Jon | |
Author | Gennari, Solange Maria | |
Access date | 2015-07-17T21:08:28Z | |
Available date | 2015-07-17T21:08:28Z | |
Document date | 2014 | |
Citation | MARCILI, Arlei et al. Phylogenetic relationships of Leishmania species based on trypanosomatid barcode (SSU rDNA) and gGAPDH genes: taxonomic revision of Leishmania (L.) infantum chagasi in South America. Infection, Genetics and Evolution, v.25, p.44–51, 2014. | pt_BR |
ISSN | 1567-1348 | |
URI | https://www.arca.fiocruz.br/handle/icict/11395 | |
Sponsorship | This work was supported by grants and fellowships from the Research Support Foundation of the State of São Paulo (Fundação de Amparo a Pesquisa do Estado de São Paulo): A.M., Grant number 2010/50886-7 and fellowship; M.A.S, Grant number 2012/20221-9; S.M.G., Grant number 2010/50839-9; C.O.C.C.S., fellowship number 2012/22732-0; A.P.C., fellowship number 2011/19853-8; and I.C.L.A., fellowship number 2011/15311-6. It was also supported by a fellowship from CNPq: A.H.H.M., fellowship number 509979/2010-6 (M.C.H.) | pt_BR |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Title | Phylogenetic relationships of Leishmania species based on trypanosomatid barcode (SSU rDNA) and gGAPDH genes: taxonomic revision of Leishmania (L.) infantum chagasi in South America | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.meegid.2014.04.001 | |
Abstract | Phylogenetic studies on trypanosomatid barcode using V7V8 SSU rRNA and gGAPDH gene sequences have provided support for redefining some trypanosomatid species and positioning new isolates. The genus Leishmania is a slow evolving monophyletic group and including important human pathogens. The phylogenetic relationships of this genus have been determined by the natural history of its vertebrate hosts, vector specificity, clinical manifestations, geographical distribution and molecular approaches using different markers. Thus, in an attempt to better understand the phylogenetic relationships of Leishmania species, we performed phylogenetic analysis on trypanosomatid barcode using V7V8 SSU rRNA and gGAPDH gene sequences among a large number of Leishmania species and also several Brazilian visceral Leishmania infantum chagasi isolates obtained from dogs and humans. Our phylogenetic analysis strongly suggested that Leishmania hertigi and Leishmania equatoriensis should be taxonomically revised so as to include them in the genus Endotrypanum; and supported ancient divergence of Leishmania enriettii. This, together with recent data in the literature, throws light on the discussion about the evolutionary southern supercontinent hypothesis for the origin of Leishmania ssp. and validates L. infantum chagasi from Brazil, thus clearly differentiating it from L. infantum, for the first time. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade Federal do ABC. Centro de Ciências Naturais e Humanas. Santo André, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade Federal do ABC. Centro de Ciências Naturais e Humanas. Santo André, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade Federal do Vale do São Franscisco. Petrolina, PE, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. São Paulo, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina Veterinária. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo, SP, Brasil | pt_BR |
Subject | Leishmania | pt_BR |
Subject | Leishmania infantum | pt_BR |
Subject | Phylogeny | pt_BR |
Subject | Classification | pt_BR |
Subject | South America | pt_BR |
DeCS | Leishmania | pt_BR |
DeCS | Leishmania infantum | pt_BR |
DeCS | Filogenia | pt_BR |
DeCS | Classificação | pt_BR |
DeCS | América do Sul | pt_BR |
e-ISSN | 1567-7257 | |