Author | Monteiro, Denise Leite Maia | |
Author | Taquette, Stella Regina | |
Author | Barmpas, Danielle Bittencourt Sodré | |
Author | Rodrigues, Nádia Cristina P | |
Author | Teixeira, Sérgio A. M | |
Author | Villela, Lucia Helena C | |
Author | Bóia, Márcio Neves | |
Author | Trajano, Alexandre José Baptista | |
Access date | 2015-04-24T18:33:06Z | |
Available date | 2015-04-24T18:33:06Z | |
Document date | 2014 | pt_BR |
Citation | MONTEIRO, Denise Leite Maia et al. Prevalence of HTLV-1/2 in Pregnant Women Living in the Metropolitan Area of Rio de Janeiro. PLOS Neglected Tropical Diseases, v.9, n.2, 5p, sept. 2014. | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/10122 | |
Language | eng | pt_BR |
Publisher | Plos One | pt_BR |
Rights | open access | pt_BR |
Title | Prevalence of HTLV-1/2 in Pregnant Women Living in the Metropolitan Area of Rio de Janeiro | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pntd.0003146 | pt_BR |
Abstract | Background: HTLV-1/2 infection can cause severe and disabling diseases in children and adults. The aim of the study was to
estimate the prevalence of HTLV-1/2 infection in pregnant women living in the metropolitan area of Rio de Janeiro.
Methodology/Principal Findings: 1,204 pregnant women were tested upon hospital admission for delivery in two public
hospitals in the cities of Rio de Janeiro and Mesquita, between November, 2012 and April, 2013. The samples were screened
by chemiluminescent microparticle immunoassay (CMIA) and reactive ones were confirmed by Western blot (WB). Epi-info
software was used for building the database and performing the statistical analysis. Eight patients had confirmed HTLV-1/2
infection (7 HTLV-1, one HTLV-2), equivalent to a prevalence rate of 0.66%. Two further reactive screening tests had negative
Western blot results and therefore were considered negative in the statistical analysis. All HTLV-1/2-positive patients were
born in Rio de Janeiro, most were non-Caucasian (87.5%), in a stable relationship (62.5%), had at least ten years of formal
education (62.5%) and a monthly family income of up to US$600.00 (87.5%). There was only one case of coinfection with
syphilis and none with HIV. The mean age of the infected women was 28.4 (SD = 6.3) years and of the seronegative ones was
24.8 (SD = 6.5) (p = 0.10). The median number of pregnancies were 3.0 and 1.0 (p = 0.06) and the median number of sexual
partners were 3.5 and 3.0 (p = 0.33) in the seropositive and negative groups, respectively. There were no statistically
significant differences between the groups.
Conclusions/Significance: A significant prevalence of HTLV-1/2 was found in our population. The socio-epidemiological
profile of carrier mothers was similar to the controls. Such findings expose the need for a public health policy of routine
HTLV-1/2 screening in antenatal care, since counselling and preventive measures are the only strategies currently available
to interrupt the chain of transmission and the future development of HTLV-1/2-related diseases. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil / Centro Universitário Serra dos Òrgãos (UNIFESO). Teresópolis, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil / Hospital Estadual da Mãe. Mesquita, RJ, Brazil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro (UERJ). Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio (UNIGRANRIO). Duque de Caxias, RJ, Brasil. | pt_BR |
Subject | Pregnant women | pt_BR |
Subject | HIV Infections | pt_BR |
Subject | Public Health | pt_BR |
Subject in Spanish | Mujeres Embarazadas | pt_BR |
Subject in Spanish | Infecciones por VIH | pt_BR |
Subject in Spanish | Salud Pública | pt_BR |
DeCS | Infecções por HIV | pt_BR |
DeCS | Gestantes | pt_BR |
DeCS | Saúde Pública | pt_BR |