Browsing by Author "Hargrove, Tatiana Y."
Now showing items 1-4 of 4
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Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi
Hoekstra, William J. et al. | Date Issued: 2016 -
CYP51 structures and structure-based development of novel, pathogen-specific inhibitory scaffolds
Hargrove, Tatiana Y. et al. | Date Issued: 2012 -
In Vitro and In Vivo Studies of the Antiparasitic Activity of Sterol 14 -Demethylase (CYP51) Inhibitor VNI against Drug-Resistant Strains of Trypanosoma cruzi
Soeiro, Maria Nazaré Correia et al. | Date Issued: 2013 -
Sterol 14α-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae
Friggeri, Laura et al. | Date Issued: 2018