Browsing by Author "Leite, Ana Cristina Lima"
Now showing items 9-28 of 39
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Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi
Costa, Lívia Bandeira et al. | Date Issued: 2016 -
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death
Moreira, Diogo Rodrigo Magalhaes et al. | Date Issued: 2014 -
Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells
Ferreira, Paulo Michel Pinheiro et al. | Date Issued: 2015Onze derivados da ftalimida foram avaliados quanto a sua atividade antiproliferativa em células tumorais e normais e possíveis efeitos tóxicos. Avaliou-se a citotoxicidade contra tumores murinos (células de Sarcoma 180 ... -
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents.
Inam, Afreen et al. | Date Issued: 2014 -
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
Santos Filho, José Maurício dos et al. | Date Issued: 2009 -
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities
Cardoso, Marcos Veríssimo de Oliveira et al. | Date Issued: 2015 -
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
Silva, Elany Barbosa da et al. | Date Issued: 2017 -
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles
Santiago, Edna de Farias et al. | Date Issued: 2014 -
In vitro and in vivo activities of multi-target phtalimido-thiazoles on Schistosomiasis mansoni
Miranda Filho, Carlos André Laranjeira et al. | Date Issued: 2020 -
Intermolecular interaction of thiosemicarbazone derivatives to solvents and a potential Aedes aegypti target
Silva, João Bosco Paraiso da et al. | Date Issued: 2015 -
Investigação Farmacológica de um novo Inibidor da Cruzaína em Modelo Animal Infectado com o Trypanosoma Cruzi (Cepa Y)
Costa, Salvana Priscylla Manso et al. | Date Issued: 2009Introdução: O desenvolvimento de novas drogas antichagásicas é uma área crucial para o combate da doença desde que o Benznidazol é ineficaz na fase crônica e de toxicidade pronunciada. Um dos mais promissores alvos para ... -
New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi
Gomes, Paulo André Teixeira de Moraes et al. | Date Issued: 2016 -
A Novel High-Content Screening-Based Method for Anti- Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Portella, Diogo Crispim Nascimento et al. | Date Issued: 2021 -
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
Gomes, Paulo André Teixeira de Moraes et al. | Date Issued: 2016 -
Phthaloyl amino acids as anti-inflammatory and immunomodulatory prototypes
Leite, Ana Cristina Lima et al. | Date Issued: 2014 -
Prospecção de novos derivados de tiossemicarbazonas na doença de chagas: avaliação in vitro do potencial tripanocida e imunomodulador de tiazóis
Silva, Ana Carla da | Date Issued: 2019A doença de Chagas (DC) afeta uma parcela significativa da população mundial, causando graves lesões. O tratamento é feito pelo uso de Benznidazol; no entanto, são necessários novos medicamentos. Neste estudo, objetivamos ... -
Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships
Donnici, Claudio Luis et al. | Date Issued: 2009 -
Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi
Oliveira Filho, Gevanio Bezerra de et al. | Date Issued: 2015 -
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2014 -
Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy
Moreira, Diogo Rodrigo Magalhaes et al. | Date Issued: 2017